Mega GLA with Sesame Lignans, 60 softgels

Gamma-linolenic acid (GLA) is an essential fatty acid (EFA) in the omega-6 family that is found primarily in plant-based oils. In the body, GLA is broken down to arachidonic acid (AA) and/or another substance called dihomogamma-liolenic acid (DGLA). Much of the GLA taken from the oils or as a supplement is not converted to AA, but rather to DGLA. DGLA competes with AA and prevents the negative inflammatory effects that AA would otherwise cause in the body. GLA, via conversion to prostaglandin E1 (PGE1), exhibits fluid-balancing and lipid-modifying potential. In addition, EFAs including GLA are important constituents of membrane phospholipids, including the mitochondrial membrane, where they enhance the integrity and the fluidity of the membrane.

Those taking anticoagulant drugs like Coumadin® (warfarin) should inform their doctor that they are taking GLA, EPA, or DHA supplements, as the physician may want to adjust the dose of anticoagulant medication based on tests that measure coagulation factors such as template bleeding time.

Since GLA, EPA, and DHA interfere with blood clotting, those who suffer from any type of hemorrhagic disease related to excessive bleeding or blood vessel leakage should consult their physician before supplementing these fatty acids.

This product should not be used by individuals who have an allergy to sesame.